High Output Podcast

Turning Model Limits Into Moats with Troy Astorino

In Turning Model Limits into Moats, Troy Astorino, Co-founder and CTO of PicnicHealth, reveals why successful AI isn't about chasing the latest models—it's about understanding where they break. 

Having built an 8 billion parameter model that outperforms larger frontier models at medical tasks, Troy shows how constraints become competitive advantages when engineered around strategically. From why engineering leaders need to get more technical during AI transitions, to building data flywheels with 350 million clinician annotations, Troy demonstrates how focusing narrow beats going wide.

Discover why the key question isn't "How fast can we ship this?" but "Where will this break?"—and how that answer determines whether you build lasting value or just expensive automation.